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BACKGROUND: Liver transplantation is a very successful therapy for thosewith end-stage disease. Although there are a lot of data about patient andgraft survival after liver transplantation, the life expectancy of and possibleloss of life (compared with a normal, matched population) in those who surviveremains unknown. AIMS: To assess the life expectancy and life-years lost ofadult liver allograft recipients, compared with an age and sex-matched UK populationto provide patients with more information and to improve use of a scareresource. METHODS: Using the National Transplant Database held by UKTransplant, on over 3,600 adult liver allograft recipients transplanted between1985 and 2003, we analysed the survival of all adults who survived more than 6months after transplantation and compared survival after transplantation withthe national age and sex matched controls to assess life-years lost. RESULTS:The estimated median survival time of the analysis cohort of 2,702 adult liverallograft recipients was 22.2 years (95% CI 19.3-25.6 years), with an estimatedloss of 7 life-years compared with an age and sex matched population.CONCLUSIONS: Overall, female recipients have a longer life expectancy and losefewer life-years than male recipients. While younger recipients have a longerlife expectancy, they also lose more life-years. Those transplanted for cancer,Hepatitis C virus infection, and alcoholic liver disease had the greatest lossof life- years. Leggil'articolo Full-textdisponibile per i soci AIGO !!!!